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gptkbp:instanceOf
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UniProt accession number
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gptkbp:alternativeName
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gptkb:Antigen_NY-CO-13
gptkb:Phosphoprotein_p53
gptkb:Tumor_suppressor_p53
gptkb:Transformation-related_protein_53
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gptkbp:associatedWith
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gptkb:Li-Fraumeni_syndrome
Various cancers
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gptkbp:biologicalProcess
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Transcription regulation
DNA-binding
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gptkbp:database
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gptkb:UniProtKB/Swiss-Prot
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gptkbp:Entrez_Gene_ID
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7157
ENSG00000141510
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gptkbp:function
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Acts as a tumor suppressor in many tumor types
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gptkbp:gene
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gptkb:TP53
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gptkbp:HGNC_ID
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11998
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https://www.w3.org/2000/01/rdf-schema#label
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P22646
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gptkbp:interactsWith
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gptkb:CDKN1A
gptkb:STAT1
gptkb:CHEK2
gptkb:CREBBP
gptkb:EP300
gptkb:HDAC10
gptkb:HDAC11
gptkb:HDAC2
gptkb:HDAC3
gptkb:HDAC4
gptkb:HDAC5
gptkb:HDAC6
gptkb:HDAC7
gptkb:HDAC8
gptkb:HDAC9
gptkb:SIRT1
gptkb:SIRT2
gptkb:SIRT3
gptkb:SIRT6
gptkb:SIRT7
gptkb:SUMO1
gptkb:SUMO2
gptkb:SUMO3
gptkb:TP53BP1
gptkb:TP53BP2
gptkb:USP7
gptkb:FAS
gptkb:SP1
gptkb:MCL1
gptkb:RB1
gptkb:CBP
gptkb:BAX
gptkb:JUN
gptkb:STAT5A
gptkb:STAT5B
gptkb:MDM2
gptkb:PTEN
gptkb:BRCA1
gptkb:CDK2
gptkb:CDK4
gptkb:CDK6
gptkb:E2F1
gptkb:HDAC1
gptkb:PML
gptkb:BCL2
gptkb:FOS
gptkb:GADD45A
gptkb:MYC
gptkb:STAT3
gptkb:TP73
gptkb:TP63
ATM
SP3
SP4
NFYA
NFYB
NFYC
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gptkbp:locatedOnChromosome
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17p13.1
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gptkbp:OMIM
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191170
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gptkbp:organism
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gptkb:Homo_sapiens
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gptkbp:pathway
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Apoptosis
p53 signaling pathway
Cell cycle regulation
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gptkbp:PDB
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gptkb:2OCJ
gptkb:3KMD
gptkb:4MZR
1TUP
5XVK
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gptkbp:postTranslationalModification
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Phosphorylation
Acetylation
Ubiquitination
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gptkbp:protein_name
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gptkb:Cellular_tumor_antigen_p53
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gptkbp:refersTo
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Human protein: Tumor protein p53
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gptkbp:sequence
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393
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gptkbp:status
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Reviewed
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gptkbp:subcellularLocation
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gptkb:Mitochondrion
gptkb:Nucleus
gptkb:Cytoplasm
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gptkbp:UniProt_entry_name
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gptkb:P53_HUMAN
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gptkbp:bfsParent
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gptkb:Cd3e
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gptkbp:bfsLayer
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8
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