|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:BCL2-associated_X_protein
gptkb:BCL2L4
|
|
gptkbp:associatedWith
|
gptkb:cancer
neurodegenerative diseases
|
|
gptkbp:biologicalProcess
|
apoptotic process
apoptosis regulator activity
protein heterodimerization activity
regulation of cell death
|
|
gptkbp:discoveredIn
|
1993
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000087088
581
|
|
gptkbp:expressedIn
|
many tissues
|
|
gptkbp:fullName
|
gptkb:BCL2_Associated_X,_Apoptosis_Regulator
|
|
gptkbp:function
|
forms heterodimers with BCL2
promotes apoptosis
|
|
gptkbp:gene
|
gptkb:BAX
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GOID
|
GO:0006915
|
|
gptkbp:hasTranscriptVariant
|
2
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:959
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
BAX
|
|
gptkbp:interactsWith
|
gptkb:BAD
gptkb:MCL1
gptkb:BID
gptkb:NOXA
gptkb:PUMA
gptkb:BAK1
gptkb:BCL-XL
gptkb:BCL2
BIM
|
|
gptkbp:length
|
192
|
|
gptkbp:locatedOnChromosome
|
19
|
|
gptkbp:location
|
19q13.33
|
|
gptkbp:molecularWeight
|
21 kDa
|
|
gptkbp:mutationAssociatedWith
|
resistance to apoptosis
|
|
gptkbp:OMIM
|
600040
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
mouse Bax
rat Bax
|
|
gptkbp:PDB
|
gptkb:1F16
|
|
gptkbp:proteinFamily
|
gptkb:BCL2_family
|
|
gptkbp:regulates
|
inhibited by BCL2
upregulated by p53
|
|
gptkbp:reviewedBy
|
gptkb:UniProtKB/Swiss-Prot
|
|
gptkbp:subcellularLocation
|
cytosol
mitochondrion outer membrane
|
|
gptkbp:UniProtID
|
gptkb:Q07812
|
|
gptkbp:bfsParent
|
gptkb:Аэропорт_Барнаул_(им._Г.С._Титова)
|
|
gptkbp:bfsLayer
|
5
|