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gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:CBP
gptkb:KAT3A
gptkb:RSTS
|
|
gptkbp:alternativeName
|
gptkb:CBP
gptkb:RSTS
|
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gptkbp:associatedWith
|
gptkb:Rubinstein-Taybi_syndrome
gptkb:acute_myeloid_leukemia
various cancers
|
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gptkbp:biologicalProcess
|
apoptosis
cell differentiation
cell growth
regulation of transcription
chromatin remodeling
transcription coactivator activity
histone acetyltransferase activity
|
|
gptkbp:cellularComponent
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gptkb:nucleus
|
|
gptkbp:discoveredBy
|
gptkb:Goodman_RH_et_al.
|
|
gptkbp:discoveredIn
|
1993
|
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gptkbp:encodes
|
gptkb:CREB-binding_protein
|
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gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000005339
1387
|
|
gptkbp:fullName
|
gptkb:CREB_binding_protein
|
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gptkbp:function
|
histone acetyltransferase
transcription coactivator
|
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gptkbp:geneType
|
protein-coding
|
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gptkbp:HGNC_ID
|
HGNC:2348
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CREBBP
|
|
gptkbp:interactsWith
|
gptkb:EP300
gptkb:p53
gptkb:CREB1
|
|
gptkbp:length
|
31 exons
|
|
gptkbp:locatedOnChromosome
|
16
16p13.3
|
|
gptkbp:mutationAssociatedWith
|
developmental disorders
cancer predisposition
|
|
gptkbp:OMIM
|
600140
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
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gptkbp:orthologInMouse
|
gptkb:Crebbp
|
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gptkbp:pathway
|
gptkb:Notch_signaling_pathway
gptkb:Wnt_signaling_pathway
gptkb:cAMP_signaling_pathway
p53 signaling pathway
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
acetylation
|
|
gptkbp:product
|
gptkb:CREB-binding_protein
|
|
gptkbp:UniProtID
|
gptkb:Q92793
|
|
gptkbp:bfsParent
|
gptkb:chromosome_16_(human)
gptkb:CREB-binding_protein
gptkb:P21554
gptkb:chromosome_16
gptkb:chromosome_16p13.3
gptkb:P53_HUMAN
gptkb:16p13.13
|
|
gptkbp:bfsLayer
|
7
|