SUMO2

GPTKB entity

Statements (50)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:SMT3B
gptkb:SUMO-2
gptkb:Sentrin-2
gptkb:Ubiquitin-like_protein_SMT3B
gptkbp:amendedBy covalent attachment
target proteins via sumoylation
gptkbp:associatedWith gptkb:cancer
heart disease
neurodegenerative diseases
gptkbp:biologicalProcess cell cycle regulation
histone modification
regulation of transcription
response to stress
gptkbp:conservedIn eukaryotes
gptkbp:discoveredIn 1996
gptkbp:Entrez_Gene_ID gptkb:ENSG00000170345
6613
gptkbp:expressedIn various tissues
gptkbp:fullName gptkb:Small_ubiquitin-related_modifier_2
gptkbp:function histone modification
protein sumoylation
gptkbp:gene gptkb:SUMO2
gptkbp:geneType protein-coding
https://www.w3.org/2000/01/rdf-schema#label SUMO2
gptkbp:interactsWith gptkb:E2_conjugating_enzyme_UBC9
gptkb:E3_ligases
gptkb:SUMO_proteases
gptkbp:length 95 amino acids
gptkbp:locatedOnChromosome gptkb:chromosome_19
19q13.32
gptkbp:location gptkb:nucleus
gptkb:cytoplasm
gptkbp:molecularWeight 11 kDa
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologIn gptkb:mouse_Sumo2
gptkb:yeast_SMT3
gptkbp:PDB gptkb:2N1W
gptkbp:postTranslationalModification conjugation to lysine residues
gptkbp:proteinFamily gptkb:SUMO_protein_family
gptkbp:RefSeq gptkb:NM_006937
gptkbp:regulates protein-protein interactions
protein localization
protein stability
gptkbp:relatedTo gptkb:SUMO1
gptkb:SUMO3
gptkbp:structure ubiquitin-like fold
gptkbp:UniProtID P61956
gptkbp:bfsParent gptkb:P21554
gptkbp:bfsLayer 7