|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
neurodegenerative diseases
|
|
gptkbp:biologicalProcess
|
histone deacetylase activity
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
|
|
gptkbp:discoveredIn
|
1999
|
|
gptkbp:encodedBy
|
gptkb:HDAC3_gene
|
|
gptkbp:enzymeCommissionNumber
|
gptkb:EC_3.5.1.98
|
|
gptkbp:fullName
|
gptkb:Histone_deacetylase_3
|
|
gptkbp:function
|
regulation of gene expression
histone deacetylation
|
|
gptkbp:gene
|
gptkb:HDAC3
|
|
gptkbp:GOID
|
GO:0004407
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HDAC3
|
|
gptkbp:interactsWith
|
gptkb:HDAC2
gptkb:HDAC1
gptkb:NCoR1
gptkb:SMRT
|
|
gptkbp:involvedIn
|
transcriptional repression
chromatin remodeling
|
|
gptkbp:length
|
428 amino acids
|
|
gptkbp:locatedOnChromosome
|
5q31
|
|
gptkbp:molecularWeight
|
49 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:PDB
|
4A69
|
|
gptkbp:target
|
HDAC inhibitors
|
|
gptkbp:UniProtID
|
gptkb:O15379
|
|
gptkbp:bfsParent
|
gptkb:vorinostat
|
|
gptkbp:bfsLayer
|
6
|