Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:HAUSP
gptkb:Ubiquitin-specific_protease_7 |
| gptkbp:associatedWith |
gptkb:cancer
neurodevelopmental disorders |
| gptkbp:encodedBy |
gptkb:USP7_gene
|
| gptkbp:enzymeCommissionNumber |
gptkb:EC_3.4.19.12
|
| gptkbp:function |
deubiquitinating enzyme
removes ubiquitin from target proteins |
| https://www.w3.org/2000/01/rdf-schema#label |
USP7
|
| gptkbp:inhibitedBy |
gptkb:FT671
gptkb:GNE-6640 P5091 |
| gptkbp:interactsWith |
gptkb:FOXO4
gptkb:PTEN gptkb:DNMT1 gptkb:ICP0_(Herpes_simplex_virus_protein) |
| gptkbp:locale |
gptkb:nucleus
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_16p13.2
|
| gptkbp:molecularWeight |
~135 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:postTranslationalModification |
phosphorylation
sumoylation |
| gptkbp:regulates |
gptkb:MDM2
gptkb:p53 DNA repair cell cycle epigenetic silencing |
| gptkbp:structure |
contains catalytic domain
contains ubiquitin-like domains |
| gptkbp:UniProtID |
gptkb:Q93009
|
| gptkbp:bfsParent |
gptkb:TP53
|
| gptkbp:bfsLayer |
6
|