|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:activatedBy
|
cytokines
growth factors
phosphorylation
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
leukemia
immune disorders
|
|
gptkbp:binds
|
gptkb:gene
|
|
gptkbp:discoveredBy
|
Darnell JE Jr. et al.
|
|
gptkbp:discoveredIn
|
1995
|
|
gptkbp:encodedBy
|
gptkb:STAT5A_gene
|
|
gptkbp:Entrez_Gene_ID
|
6776
ENSG00000126561
|
|
gptkbp:expressedIn
|
various tissues
mammary gland
immune cells
|
|
gptkbp:function
|
transcription factor
signal transducer
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasParalog
|
gptkb:STAT5B
|
|
gptkbp:hasRefSeqID
|
NM_003152
|
|
gptkbp:HGNC_ID
|
11366
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
STAT5A
|
|
gptkbp:interactsWith
|
gptkb:JAK2
gptkb:GRB2
gptkb:STAT3
gptkb:NCOA1
|
|
gptkbp:involvedIn
|
gptkb:JAK-STAT_signaling_pathway
apoptosis
cell proliferation
immune response
prolactin signaling pathway
mammary gland development
|
|
gptkbp:locatedOnChromosome
|
17q21.2
|
|
gptkbp:memberOf
|
gptkb:STAT_protein_family
|
|
gptkbp:molecularWeight
|
approximately 90 kDa
|
|
gptkbp:orthologInMouse
|
gptkb:Stat5a
|
|
gptkbp:phosphorylates
|
Y694
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
acetylation
|
|
gptkbp:regulates
|
gene expression
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
P42229
|
|
gptkbp:bfsParent
|
gptkb:JAK-STAT_signaling_pathway
gptkb:STAT_pathway
gptkb:STATs
gptkb:STAT_proteins
gptkb:JAK-STAT_pathway
gptkb:JAK/STAT_signaling_pathway
|
|
gptkbp:bfsLayer
|
7
|