Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic disorder
hereditary cancer syndrome |
| gptkbp:affects |
adults
children |
| gptkbp:characteristic |
family history of cancer
multiple primary cancers early onset of cancer |
| gptkbp:diagnosedBy |
genetic testing
|
| gptkbp:firstDescribed |
gptkb:Frederick_P._Li
gptkb:Joseph_F._Fraumeni_Jr. 1969 |
| https://www.w3.org/2000/01/rdf-schema#label |
Li-Fraumeni syndrome
|
| gptkbp:ICD-10_code |
Q85.8
|
| gptkbp:inheritance |
autosomal dominant
|
| gptkbp:managedBy |
genetic counseling
cancer surveillance risk-reducing surgery |
| gptkbp:MeSH_ID |
D018949
|
| gptkbp:mutationAssociatedWith |
gptkb:TP53_gene
|
| gptkbp:OMIM |
151623
|
| gptkbp:prevalence |
rare
|
| gptkbp:riskFactor |
gptkb:cancer
gptkb:rhabdomyosarcoma leukemia adrenocortical carcinoma osteosarcoma brain tumors |
| gptkbp:synonym |
gptkb:LFS
gptkb:SBLA_syndrome |
| gptkbp:bfsParent |
gptkb:rhabdomyosarcoma
|
| gptkbp:bfsLayer |
5
|