Transformation-related protein 53

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alsoKnownAs	gptkb:p53
gptkbp:discoveredBy	gptkb:Lloyd_Old gptkb:Arnold_J._Levine gptkb:David_Lane
gptkbp:encodedBy	gptkb:TP53_gene
gptkbp:foundIn	gptkb:Homo_sapiens
gptkbp:function	tumor suppressor transcription factor
https://www.w3.org/2000/01/rdf-schema#label	Transformation-related protein 53
gptkbp:interactsWith	gptkb:BAX gptkb:p21 gptkb:MDM2 ATM
gptkbp:locatedOnChromosome	17p13.1
gptkbp:molecularWeight	~53 kDa
gptkbp:mutationAssociatedWith	gptkb:cancer
gptkbp:postTranslationalModification	phosphorylation ubiquitination acetylation
gptkbp:regulates	gptkb:CDKN1A gptkb:XPC gptkb:FAS gptkb:PERP gptkb:BAX gptkb:DDB2 gptkb:GADD45 gptkb:GDF15 gptkb:IGFBP3 gptkb:NOXA gptkb:PIG3 gptkb:PUMA gptkb:RRM2B gptkb:SESN1 gptkb:SESN2 gptkb:TIGAR gptkb:DR5 gptkb:MDM2 gptkb:PTEN gptkb:BCL2 gptkb:14-3-3σ gptkb:P53AIP1 gptkb:P53DINP1 gptkb:P53INP1 gptkb:P53R2 gptkb:P53RDL1 gptkb:P53RDL2 gptkb:P53RDL3 gptkb:P53RDL4 gptkb:P53RDL9 apoptosis DNA repair cell cycle senescence P53RDL10 P53RDL11 P53RDL12 P53RDL13 P53RDL14 P53RDL15 P53RDL16 P53RDL17 P53RDL18 P53RDL19 P53RDL20 P53RDL5 P53RDL6 P53RDL7 P53RDL8
gptkbp:structure	tetramer
gptkbp:UniProtID	P04637
gptkbp:bfsParent	gptkb:P04629 gptkb:P23560
gptkbp:bfsLayer	7