|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
neurodegenerative diseases
cardiac hypertrophy
|
|
gptkbp:encodedBy
|
gptkb:HDAC5_gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000072501
10014
|
|
gptkbp:expressedIn
|
gptkb:leukocytes
gptkb:cancer
gptkb:skeletal_muscle
gptkb:kidney
gptkb:placenta
gptkb:prostate
gptkb:small_intestine
gptkb:testis
gptkb:thymus
brain
heart
liver
spleen
colon
pancreas
|
|
gptkbp:fullName
|
gptkb:Histone_deacetylase_5
|
|
gptkbp:function
|
histone deacetylation
transcriptional repression
|
|
gptkbp:geneType
|
protein-coding
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HDAC5
|
|
gptkbp:inhibitedBy
|
HDAC inhibitors
|
|
gptkbp:interactsWith
|
gptkb:14-3-3_proteins
gptkb:MEF2C
gptkb:HDAC3
gptkb:MEF2A
gptkb:MEF2D
|
|
gptkbp:length
|
1122 amino acids
|
|
gptkbp:locatedOnChromosome
|
17q21.31
|
|
gptkbp:memberOf
|
histone deacetylase family
|
|
gptkbp:memberOfClass
|
gptkb:Class_IIa_HDAC
|
|
gptkbp:molecularWeight
|
~112 kDa
|
|
gptkbp:OMIM
|
605314
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Hdac5
|
|
gptkbp:phosphorylates
|
gptkb:PKD
gptkb:CaMK
|
|
gptkbp:regulates
|
gene expression
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
gptkb:Q9UQL6
|
|
gptkbp:bfsParent
|
gptkb:Histone_deacetylase
gptkb:P21554
|
|
gptkbp:bfsLayer
|
7
|