PTEN

GPTKB entity

Statements (55)
Predicate Object
gptkbp:instanceOf gene
gptkbp:aftermath cellular signaling
gptkbp:associatedWith gptkb:Cowden_syndrome
gptkb:Lhermitte-Duclos_disease
gptkb:Bannayan-Riley-Ruvalcaba_syndrome
cancer
gptkbp:bornIn breast cancer
prostate cancer
endometrial cancer
gptkbp:diedIn cell cycle regulation
gptkbp:function tumor suppressor
gptkbp:hasPrograms mouse
zebrafish
worm
rat
fruit fly
gptkbp:hasRole immune response
neurogenesis
https://www.w3.org/2000/01/rdf-schema#label PTEN
gptkbp:interactsWith gptkb:AKT
gptkb:EGFR
gptkb:PDGF
mTOR
gptkbp:involvedIn metabolism
DNA repair
apoptosis
angiogenesis
cell migration
gptkbp:is_evaluated_by testis
brain
gptkbp:isActiveIn PI3K/AKT signaling pathway
gptkbp:isFoundIn tumor tissues
normal tissues
gptkbp:isInvolvedIn diabetes
cellular homeostasis
cellular metabolism
metabolic disorders
signal transduction
inflammation
cardiovascular diseases
oxidative stress response
tumor microenvironment
cellular differentiation
stem cell maintenance
neurodevelopmental disorders
gptkbp:isLinkedTo tumorigenesis
gptkbp:isRegulatedBy phosphorylation
ubiquitination
microRNAs
gptkbp:isStudiedIn clinical trials
gptkbp:isTargetedAt cancer therapies
gptkbp:isUtilizedFor embryonic development
gptkbp:locatedIn chromosome 10
gptkbp:regulates cell growth
cell survival