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gptkbp:instanceOf
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UniProt accession number
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gptkbp:alternativeName
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gptkb:Antigen_NY-CO-13
gptkb:Phosphoprotein_p53
gptkb:Tumor_suppressor_p53
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gptkbp:biologicalProcess
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DNA repair
Apoptosis
DNA-binding
Cell cycle arrest
Cellular response to stress
Transcription factor activity
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gptkbp:database
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gptkb:UniProtKB/Swiss-Prot
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gptkbp:function
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Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type.
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gptkbp:gene
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gptkb:TP53
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https://www.w3.org/2000/01/rdf-schema#label
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P21554
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gptkbp:interactsWith
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gptkb:ATR
gptkb:CDKN1A
gptkb:CASP8
gptkb:CASP9
gptkb:CHEK2
gptkb:CREBBP
gptkb:EP300
gptkb:HDAC10
gptkb:HDAC11
gptkb:HDAC2
gptkb:HDAC3
gptkb:HDAC4
gptkb:HDAC5
gptkb:HDAC6
gptkb:HDAC7
gptkb:HDAC8
gptkb:HDAC9
gptkb:SIRT1
gptkb:SIRT2
gptkb:SIRT3
gptkb:SIRT6
gptkb:SIRT7
gptkb:SUMO1
gptkb:SUMO2
gptkb:SUMO3
gptkb:TP53BP1
gptkb:TP53BP2
gptkb:TP53INP1
gptkb:TP53INP2
gptkb:TP53RK
gptkb:TP53TG1
gptkb:TP53TG10
gptkb:TP53TG11
gptkb:TP53TG12
gptkb:TP53TG13
gptkb:TP53TG14
gptkb:TP53TG15
gptkb:TP53TG16
gptkb:TP53TG17
gptkb:TP53TG18
gptkb:TP53TG19
gptkb:TP53TG20
gptkb:TP53TG21
gptkb:TP53TG22
gptkb:TP53TG23
gptkb:TP53TG24
gptkb:TP53TG25
gptkb:TP53TG26
gptkb:TP53TG27
gptkb:TP53TG28
gptkb:TP53TG29
gptkb:TP53TG3
gptkb:TP53TG30
gptkb:TP53TG31
gptkb:TP53TG32
gptkb:TP53TG33
gptkb:TP53TG34
gptkb:TP53TG35
gptkb:TP53TG36
gptkb:TP53TG37
gptkb:TP53TG38
gptkb:TP53TG39
gptkb:TP53TG40
gptkb:TP53TG5
gptkb:TP53TG6
gptkb:TP53TG7
gptkb:TP53TG8
gptkb:TP53TG9
gptkb:USP10
gptkb:USP7
gptkb:FAS
gptkb:RB1
gptkb:BAX
gptkb:MDM2
gptkb:BRCA1
gptkb:E2F1
gptkb:HDAC1
gptkb:BCL2
gptkb:GADD45A
ATM
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gptkbp:locatedOnChromosome
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17
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gptkbp:location
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17p13.1
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gptkbp:organism
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gptkb:Homo_sapiens
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gptkbp:pathology
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Mutations associated with Li-Fraumeni syndrome
Mutations associated with various cancers
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gptkbp:postTranslationalModification
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Phosphorylation
Acetylation
Ubiquitination
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gptkbp:protein_name
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gptkb:Cellular_tumor_antigen_p53
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gptkbp:refersTo
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gptkb:Tumor_protein_p53_(human)
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gptkbp:sequence
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393
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gptkbp:status
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Reviewed
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gptkbp:structure
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Tetramer
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gptkbp:subcellularLocation
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gptkb:Mitochondrion
gptkb:Nucleus
gptkb:Cytoplasm
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gptkbp:bfsParent
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gptkb:CB1
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gptkbp:bfsLayer
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6
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