|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:p53
gptkb:tumor_protein_p53
|
|
gptkbp:discoveredBy
|
gptkb:Arnold_Levine
gptkb:Lloyd_Old
gptkb:David_Lane
|
|
gptkbp:discoveredIn
|
1979
|
|
gptkbp:domain
|
DNA-binding domain
oligomerization domain
transactivation domain
|
|
gptkbp:encodes
|
gptkb:cellular_tumor_antigen_p53
|
|
gptkbp:Entrez_Gene_ID
|
7157
ENSG00000141510
|
|
gptkbp:function
|
tumor suppressor
transcription factor
|
|
gptkbp:HGNC_ID
|
11998
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TRP53
|
|
gptkbp:length
|
393 amino acids
|
|
gptkbp:locatedOnChromosome
|
17p13.1
|
|
gptkbp:mutationAssociatedWith
|
gptkb:Li-Fraumeni_syndrome
various cancers
|
|
gptkbp:OMIM
|
191170
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:product
|
gptkb:p53_protein
|
|
gptkbp:regulates
|
gptkb:FAS
gptkb:PERP
gptkb:CD82
gptkb:BAX
gptkb:DDB2
gptkb:GADD45
gptkb:IGFBP3
gptkb:NOXA
gptkb:PIG3
gptkb:PUMA
gptkb:RRM2B
gptkb:SESN1
gptkb:TIGAR
gptkb:DR5
gptkb:MDM2
gptkb:PTEN
gptkb:BCL2
gptkb:S100A2
gptkb:p21_(CDKN1A)
gptkb:P53TG1
gptkb:14-3-3σ
gptkb:P53AIP1
gptkb:P53DINP1
gptkb:P53INP1
gptkb:P53R2
apoptosis
DNA repair
cell cycle
senescence
genomic stability
P53TG10
P53TG12
P53TG13
P53TG14
P53TG15
P53TG16
P53TG17
P53TG18
P53TG19
P53TG20
P53TG21
P53TG22
P53TG23
P53TG24
P53TG25
P53TG26
P53TG27
P53TG28
P53TG29
P53TG3
P53TG30
P53TG31
P53TG32
P53TG33
P53TG34
P53TG35
P53TG36
P53TG37
P53TG38
P53TG39
P53TG40
P53TG41
P53TG42
P53TG43
P53TG44
P53TG45
P53TG46
P53TG47
P53TG48
P53TG49
P53TG5
P53TG50
P53TG7
P53TG8
REDD1
miR-34
|
|
gptkbp:UniProtID
|
P04637
|
|
gptkbp:bfsParent
|
gptkb:HGNC:12363
gptkb:ENSG00000141448
|
|
gptkbp:bfsLayer
|
7
|