|
gptkbp:instanceOf
|
gptkb:Ensembl_gene_ID
|
|
gptkbp:alias
|
gptkb:BCC7
gptkb:LFS1
gptkb:TRP53
P53
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:Li-Fraumeni_syndrome
|
|
gptkbp:chromosomeArm
|
p
|
|
gptkbp:discoveredBy
|
gptkb:Arnold_Levine
gptkb:Lloyd_Old
gptkb:David_Lane
|
|
gptkbp:discoveredIn
|
1979
|
|
gptkbp:encodes
|
gptkb:cellular_tumor_antigen_p53
|
|
gptkbp:Entrez_Gene_ID
|
7157
|
|
gptkbp:expressedIn
|
many tissues
|
|
gptkbp:function
|
gptkb:transcription_factor
gptkb:tumor_suppressor
|
|
gptkbp:gene
|
gptkb:TP53
|
|
gptkbp:geneType
|
protein_coding
|
|
gptkbp:hasParalog
|
gptkb:TP73
gptkb:TP63
|
|
gptkbp:HGNC_ID
|
11998
|
|
gptkbp:locatedOnChromosome
|
17
17p13.1
|
|
gptkbp:mutationAssociatedWith
|
increased cancer risk
|
|
gptkbp:OMIM
|
191170
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:pathway
|
apoptosis
cell cycle regulation
p53 signaling pathway
|
|
gptkbp:product
|
P04637
|
|
gptkbp:referenceGenome
|
gptkb:GRCh38
|
|
gptkbp:regulates
|
apoptosis
DNA repair
metabolism
angiogenesis
senescence
cell cycle arrest
|
|
gptkbp:startPoint
|
7661779
7687550
|
|
gptkbp:strand
|
minus
|
|
gptkbp:transcriptCount
|
15
|
|
gptkbp:UniProtID
|
P04637
|
|
gptkbp:bfsParent
|
gptkb:COL13A1
gptkb:COL14A1
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ENSG00000119699
|