|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:p53
gptkb:BCC7
gptkb:LFS1
gptkb:TRP53
|
|
gptkbp:associatedWith
|
gptkb:Li-Fraumeni_syndrome
various cancers
|
|
gptkbp:discoveredBy
|
gptkb:Lloyd_Old
gptkb:Arnold_J._Levine
gptkb:David_Lane
|
|
gptkbp:encodes
|
gptkb:cellular_tumor_antigen_p53
|
|
gptkbp:Entrez_Gene_ID
|
7157
ENSG00000141510
|
|
gptkbp:function
|
apoptosis
tumor suppressor
DNA repair
regulation of cell cycle
genomic stability
|
|
gptkbp:HGNC_ID
|
11998
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
human TP53
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_17
17p13.1
|
|
gptkbp:mutationAssociatedWith
|
increased cancer risk
|
|
gptkbp:OMIM
|
191170
|
|
gptkbp:orthologInMouse
|
gptkb:Trp53
|
|
gptkbp:product
|
gptkb:p53_protein
|
|
gptkbp:regulates
|
gptkb:CDKN1A
gptkb:TP53BP1
gptkb:TP53BP2
gptkb:TP53INP1
gptkb:TP53TG1
gptkb:TP53TG10
gptkb:TP53TG11
gptkb:TP53TG12
gptkb:TP53TG13
gptkb:TP53TG14
gptkb:TP53TG15
gptkb:TP53TG16
gptkb:TP53TG17
gptkb:TP53TG18
gptkb:TP53TG19
gptkb:TP53TG20
gptkb:TP53TG21
gptkb:TP53TG22
gptkb:TP53TG23
gptkb:TP53TG24
gptkb:TP53TG25
gptkb:TP53TG26
gptkb:TP53TG27
gptkb:TP53TG28
gptkb:TP53TG29
gptkb:TP53TG3
gptkb:TP53TG30
gptkb:TP53TG31
gptkb:TP53TG32
gptkb:TP53TG33
gptkb:TP53TG34
gptkb:TP53TG35
gptkb:TP53TG36
gptkb:TP53TG37
gptkb:TP53TG38
gptkb:TP53TG39
gptkb:TP53TG40
gptkb:TP53TG5
gptkb:TP53TG6
gptkb:TP53TG7
gptkb:TP53TG8
gptkb:TP53TG9
gptkb:FAS
gptkb:PERP
gptkb:FASLG
gptkb:BAX
gptkb:DDB2
gptkb:IGFBP3
gptkb:NOXA
gptkb:PIG3
gptkb:PUMA
gptkb:RRM2B
gptkb:SESN1
gptkb:TIGAR
gptkb:GML
gptkb:DR5
gptkb:MDM2
gptkb:PTEN
gptkb:SFN
gptkb:GADD45A
gptkb:BCL2L11
gptkb:14-3-3σ
gptkb:P53R2
true
BBC3
P21
APAF1
PMAIP1
TP53AIP1
TP53TG3B
TP53TG3C
TP53TG3D
TP53TG3E
TP53TG3F
TP53TG3G
TP53TG3H
TP53TG3I
TP53TG3J
TP53TG3K
TP53TG3L
TP53TG3M
TP53TG3N
TP53TG3O
TP53TG3P
TP53TG3Q
TP53TG3R
TP53TG3S
TP53TG3T
TP53TG3U
TP53TG3V
TP53TG3W
TP53TG3X
TP53TG3Y
TP53TG3Z
TP53TG4
|
|
gptkbp:UniProtID
|
P04637
|
|
gptkbp:bfsParent
|
gptkb:NP_031401
|
|
gptkbp:bfsLayer
|
7
|