|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:KAI1
R2
|
|
gptkbp:associatedWith
|
cancer progression
|
|
gptkbp:component
|
integral component of membrane
extracellular exosome
|
|
gptkbp:discoveredBy
|
gptkb:Dong_et_al.
|
|
gptkbp:discoveredIn
|
1995
|
|
gptkbp:downregulatedIn
|
gptkb:cancer
prostate cancer
colon cancer
|
|
gptkbp:encodedBy
|
gptkb:CD82_gene
|
|
gptkbp:Entrez_Gene_ID
|
3732
ENSG00000177697
|
|
gptkbp:expressedIn
|
gptkb:leukocytes
epithelial cells
|
|
gptkbp:function
|
cell signaling
cell adhesion
protein binding
cell adhesion molecule binding
tumor metastasis suppressor
|
|
gptkbp:GOProcess
|
negative regulation of cell proliferation
negative regulation of cell migration
|
|
gptkbp:HGNC_ID
|
HGNC:620
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CD82
|
|
gptkbp:interactsWith
|
gptkb:EGFR
gptkb:CD63
gptkb:CD9
gptkb:integrins
gptkb:CD19
gptkb:CD81
|
|
gptkbp:locatedOnChromosome
|
gptkb:11p11.2
|
|
gptkbp:location
|
gptkb:plasma_membrane
exosomes
|
|
gptkbp:memberOf
|
tetraspanin family
|
|
gptkbp:OMIM
|
600623
|
|
gptkbp:orthologInMouse
|
gptkb:Cd82
|
|
gptkbp:postTranslationalModification
|
palmitoylation
glycosylation
|
|
gptkbp:regulates
|
cell motility
cell invasion
cell-cell interactions
|
|
gptkbp:significance
|
biomarker for cancer prognosis
|
|
gptkbp:UniProtID
|
P27701
|
|
gptkbp:bfsParent
|
gptkb:CD81
|
|
gptkbp:bfsLayer
|
7
|