|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:MTP53R2
gptkb:p53R2
|
|
gptkbp:associated_protein_complex
|
gptkb:ribonucleotide_reductase_complex
|
|
gptkbp:associatedWith
|
gptkb:mitochondrial_DNA_depletion_syndrome
gptkb:progressive_external_ophthalmoplegia
sensorineural hearing loss
renal tubulopathy
|
|
gptkbp:chromosomeArm
|
8q22.3
|
|
gptkbp:discoveredIn
|
2001
|
|
gptkbp:encodes
|
gptkb:p53-inducible_ribonucleotide_reductase_small_subunit
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000171843
50484
|
|
gptkbp:expressedIn
|
ubiquitous
upregulated by DNA damage
|
|
gptkbp:fullName
|
gptkb:ribonucleotide_reductase_regulatory_TP53_inducible_subunit_M2B
|
|
gptkbp:function
|
DNA repair
mitochondrial DNA maintenance
deoxyribonucleotide synthesis
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:10451
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
RRM2B
|
|
gptkbp:locatedOnChromosome
|
8
|
|
gptkbp:mutationAssociatedWith
|
mitochondrial DNA depletion
|
|
gptkbp:OMIM
|
604712
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:mouse_Rrm2b
|
|
gptkbp:pathway
|
DNA damage response
nucleotide metabolism
|
|
gptkbp:product
|
gptkb:Ribonucleoside-diphosphate_reductase_subunit_M2_B
|
|
gptkbp:regulates
|
induced by p53
|
|
gptkbp:UniProtID
|
gptkb:Q7LG56
|
|
gptkbp:bfsParent
|
gptkb:p53
|
|
gptkbp:bfsLayer
|
6
|