Statements (63)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:DNA
|
| gptkbp:associated_with |
stress response
|
| gptkbp:form |
gptkb:GADD45_A
gptkb:GADD45_B gptkb:GADD45_G |
| gptkbp:has_function |
tumor suppression
|
| gptkbp:has_role |
inflammation
|
| https://www.w3.org/2000/01/rdf-schema#label |
GADD45
|
| gptkbp:influences |
gene expression
|
| gptkbp:interacts_with |
MAPK pathway
|
| gptkbp:involved_in |
DNA repair
apoptosis cell cycle regulation cellular stress response |
| gptkbp:is_associated_with |
autoimmune diseases
chronic diseases chronic stress tumorigenesis chronic inflammation |
| gptkbp:is_expressed_in |
gptkb:Cell
various tissues embryogenesis cancerous tissues muscle tissues skin tissues pancreatic tissues adipose tissues brain tissues liver tissues |
| gptkbp:is_induced_by |
DNA damage
|
| gptkbp:is_involved_in |
gptkb:neurodegenerative_diseases
reproductive health cell differentiation cellular homeostasis cellular metabolism immune response metabolic pathways signal transduction wound healing cellular proliferation cellular senescence tissue regeneration neural development cellular signaling pathways cellular communication cellular signaling cellular repair mechanisms cellular adaptation cellular detoxification response to oxidative stress |
| gptkbp:is_linked_to |
aging
metabolic disorders metabolic syndrome neuroinflammation cardiovascular diseases |
| gptkbp:is_located_in |
gptkb:chromosome_1
|
| gptkbp:is_part_of |
gptkb:GADD45_family
|
| gptkbp:is_regulated_by |
gptkb:p53
cytokines |
| gptkbp:is_studied_in |
cancer research
|
| gptkbp:is_targeted_at |
therapeutic agents
|
| gptkbp:bfsParent |
gptkb:p53
|
| gptkbp:bfsLayer |
6
|