|
gptkbp:instanceOf
|
gptkb:Ensembl_gene_ID
|
|
gptkbp:alias
|
gptkb:p53
gptkb:BCC7
gptkb:LFS1
gptkb:TRP53
P53 tumor suppressor
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:Li-Fraumeni_syndrome
gptkb:bladder_cancer
colorectal cancer
osteosarcoma
hepatocellular carcinoma
|
|
gptkbp:encodes
|
gptkb:TP53
|
|
gptkbp:Entrez_Gene_ID
|
7157
|
|
gptkbp:function
|
gptkb:transcription_factor
gptkb:tumor_suppressor
DNA repair
senescence
apoptosis regulation
cell cycle arrest
metabolism regulation
DNA binding
angiogenesis inhibition
|
|
gptkbp:gene
|
gptkb:TP53
|
|
gptkbp:geneType
|
protein_coding
|
|
gptkbp:hasTranscript
|
gptkb:ENST00000269305
ENST00000413465
ENST00000420246
ENST00000445888
|
|
gptkbp:HGNC_ID
|
HGNC:11998
|
|
gptkbp:length
|
19149
|
|
gptkbp:locatedOnChromosome
|
17
17p13.1
|
|
gptkbp:OMIM
|
191170
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Trp53
gptkb:Tp53
|
|
gptkbp:orthologInZebrafish
|
tp53
|
|
gptkbp:referenceGenome
|
gptkb:GRCh37
gptkb:GRCh38
|
|
gptkbp:regulates
|
apoptosis
DNA repair
cell cycle
|
|
gptkbp:startPoint
|
7687550
7668402
|
|
gptkbp:strand
|
negative
|
|
gptkbp:tissue_specificity
|
ubiquitous
|
|
gptkbp:UniProtID
|
P04637
|
|
gptkbp:bfsParent
|
gptkb:MIB1_(human_gene)
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ENSG00000141424
|