Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:TNFRSF10B
gptkb:TRAIL_receptor_2 |
| gptkbp:binds |
gptkb:TRAIL
|
| gptkbp:contains |
death domain
|
| gptkbp:discoveredIn |
late 1990s
|
| gptkbp:downregulatedIn |
gptkb:NF-kB
|
| gptkbp:encodedBy |
gptkb:TNFRSF10B_gene
|
| gptkbp:expressedIn |
various human tissues
|
| gptkbp:function |
induces apoptosis
|
| https://www.w3.org/2000/01/rdf-schema#label |
DR5
|
| gptkbp:involvedIn |
cell death signaling pathway
|
| gptkbp:involves |
cancer therapy research
|
| gptkbp:locatedIn |
gptkb:cell_membrane
|
| gptkbp:memberOf |
gptkb:tumor_necrosis_factor_receptor_superfamily
|
| gptkbp:orthologIn |
gptkb:mouse
right |
| gptkbp:regulates |
apoptosis in response to TRAIL
|
| gptkbp:structure |
transmembrane protein
|
| gptkbp:UniProtID |
gptkb:O14763
|
| gptkbp:upregulatedBy |
gptkb:p53
|
| gptkbp:bfsParent |
gptkb:Sloan_Digital_Sky_Survey
gptkb:p53 gptkb:Sloan_Digital_Sky_Survey_(SDSS) |
| gptkbp:bfsLayer |
6
|