|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:AML1
gptkb:CBFA2
gptkb:PEBP2A2
|
|
gptkbp:associatedWith
|
gptkb:acute_myeloid_leukemia
gptkb:familial_platelet_disorder_with_propensity_to_myeloid_malignancy
myelodysplastic syndrome
|
|
gptkbp:discoveredBy
|
gptkb:Yoshida_et_al.
|
|
gptkbp:encodes
|
gptkb:Runt-related_transcription_factor_1
|
|
gptkbp:Entrez_Gene_ID
|
861
ENSG00000159216
|
|
gptkbp:expressedIn
|
hematopoietic stem cells
|
|
gptkbp:function
|
transcription factor
|
|
gptkbp:HGNC_ID
|
10471
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
RUNX1
|
|
gptkbp:interactsWith
|
gptkb:SMAD3
gptkb:GATA1
gptkb:CBFβ
gptkb:ETS1
gptkb:p300
|
|
gptkbp:involvedIn
|
hematopoiesis
|
|
gptkbp:locatedOnChromosome
|
chromosome 21
|
|
gptkbp:memberOf
|
gptkb:RUNX_family
|
|
gptkbp:mutationAssociatedWith
|
gptkb:translocation_t(8;21)
point mutation
|
|
gptkbp:OMIM
|
151385
|
|
gptkbp:orthologInMouse
|
gptkb:Runx1
|
|
gptkbp:orthologInZebrafish
|
runx1
|
|
gptkbp:proteinFamily
|
Runt domain
|
|
gptkbp:regulates
|
gptkb:GATA2
gptkb:CD56
gptkb:CD45
gptkb:CD34
gptkb:CD10
gptkb:CD13
gptkb:CD41
gptkb:CD61
gptkb:MYB
gptkb:CD33
gptkb:CD19
gptkb:CD4
gptkb:MPL
gptkb:CD14
gptkb:CD117
gptkb:CD123
gptkb:CD135
gptkb:CD184
gptkb:CD195
gptkb:CD300A
gptkb:CD36
gptkb:CD38
gptkb:CD42
gptkb:CD7
gptkb:CD71
gptkb:CD79A
gptkb:CD8A
gptkb:CD8B
gptkb:CSF1R
gptkb:IL3
gptkb:PU.1
gptkb:TCRB
gptkb:CD3E
gptkb:CD274
gptkb:CD302
gptkb:CD320
gptkb:CD200
gptkb:CD244
gptkb:CD366
gptkb:CD371
gptkb:CD372
gptkb:CD373
gptkb:CD374
gptkb:CD375
gptkb:CD376
gptkb:CD377
gptkb:CD378
gptkb:CD379
gptkb:CD380
gptkb:CD381
gptkb:CD382
gptkb:CD383
gptkb:CD384
gptkb:CD385
gptkb:CD386
gptkb:CD387
gptkb:CD388
gptkb:CD389
gene expression
CD2
CD5
CD390
CD391
CD392
CD393
CD394
CD395
CD396
CD397
CD398
CD399
core consensus sequence TGTGGT
|
|
gptkbp:UniProtID
|
Q01196
|
|
gptkbp:bfsParent
|
gptkb:RUNX1_mutation
gptkb:21q22.11
|
|
gptkbp:bfsLayer
|
6
|