CD117

URI: https://gptkb.org/entity/CD117

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alsoKnownAs	gptkb:KIT gptkb:c-Kit
gptkbp:discoveredIn	1987
gptkbp:encodedBy	gptkb:KIT_gene
gptkbp:expressedIn	gptkb:mast_cells gptkb:interstitial_cells_of_Cajal gptkb:germ_cells hematopoietic stem cells
gptkbp:function	gptkb:receptor_tyrosine_kinase
gptkbp:HGNC_ID	6342
https://www.w3.org/2000/01/rdf-schema#label	CD117
gptkbp:ligand	gptkb:stem_cell_factor
gptkbp:locatedOnChromosome	gptkb:chromosome_4
gptkbp:location	gptkb:cell_membrane
gptkbp:marking	gptkb:mast_cell_disease gptkb:acute_myeloid_leukemia gastrointestinal stromal tumors
gptkbp:molecularWeight	145 kDa
gptkbp:mutationAssociatedWith	gptkb:mastocytosis gptkb:acute_myeloid_leukemia gastrointestinal stromal tumors
gptkbp:targetOfDrug	gptkb:dasatinib gptkb:imatinib gptkb:sunitinib
gptkbp:UniProtID	P10721
gptkbp:bfsParent	gptkb:gastrointestinal_stromal_tumor gptkb:MGTA-117 gptkb:Stem_Cell_Factor gptkb:c-KIT gptkb:GIST gptkb:RUNX1 gptkb:c-Kit
gptkbp:bfsLayer	7