CD79A

GPTKB entity

Statements (50)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:gene
gptkbp:alternativeName gptkb:Ig-alpha
gptkb:MB-1
Immunoglobulin-associated alpha
gptkbp:associatedWith B-cell development
gptkbp:component gptkb:B-cell_receptor_complex
gptkbp:discoveredIn 1988
gptkbp:domain Ig-like domain
ITAM motif
gptkbp:encodes B-cell antigen receptor complex-associated protein alpha chain
gptkbp:Entrez_Gene_ID 973
gptkbp:expressedIn gptkb:B_lymphocytes
early B-cell development
gptkbp:formsComplexWith gptkb:CD79B
gptkbp:function signal transduction in B cells
gptkbp:geneType protein-coding
gptkbp:hasTranscriptVariant multiple
gptkbp:HGNC_ID HGNC:1699
https://www.w3.org/2000/01/rdf-schema#label CD79A
gptkbp:interactsWith gptkb:BLNK
gptkb:LYN
SYK
gptkbp:length 226 amino acids
gptkbp:locatedOnChromosome gptkb:chromosome_19
19q13.2
gptkbp:marking B-cell lineage in immunohistochemistry
gptkbp:molecularWeight 26 kDa
gptkbp:mutationAssociatedWith agammaglobulinemia-3
gptkbp:OMIM 112205
gptkbp:orthologInCat gptkb:CD79A
gptkbp:orthologInChicken gptkb:CD79A
gptkbp:orthologInCow gptkb:CD79A
gptkbp:orthologInDog gptkb:CD79A
gptkbp:orthologInFrog cd79a
gptkbp:orthologInHorse gptkb:CD79A
gptkbp:orthologInMouse Cd79a
gptkbp:orthologInPig gptkb:CD79A
gptkbp:orthologInSheep gptkb:CD79A
gptkbp:orthologInXenopus cd79a
gptkbp:orthologInZebrafish cd79a
gptkbp:phosphorylates Src-family kinases
gptkbp:requires B-cell signaling
BCR surface expression
gptkbp:subcellularLocation gptkb:cell_membrane
gptkb:plasma_membrane
gptkbp:UniProtID P11912
gptkbp:bfsParent gptkb:RUNX1
gptkb:PAX5
gptkbp:bfsLayer 7