Statements (97)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
transferrin receptor protein 1
|
| gptkbp:antibodyTarget |
immunophenotyping
|
| gptkbp:expressedIn |
gptkb:breast
gptkb:cervix gptkb:endometrium gptkb:fallopian_tube gptkb:gallbladder gptkb:thyroid gptkb:cancer gptkb:NK_cells gptkb:hepatocytes gptkb:bone gptkb:skin gptkb:pituitary_gland gptkb:skeletal_muscle gptkb:B_cells gptkb:T_cells gptkb:adrenal_gland gptkb:kidney gptkb:placenta gptkb:prostate gptkb:small_intestine gptkb:spinal_cord gptkb:testis gptkb:thymus gptkb:osteoclasts gptkb:urinary_bladder gptkb:germ_cells gptkb:microglia gptkb:megakaryocytes gptkb:spermatogonia gptkb:oligodendrocytes brain heart retina liver collagen spleen tonsil adipose tissue bone marrow colon esophagus lymph node pancreas parathyroid gland salivary gland stomach uterus neurons dendritic cells macrophages Schwann cells appendix endothelial cells fibroblasts astrocytes monocytes epithelial cells hematopoietic stem cells granulocytes peripheral blood leukocytes chondrocytes erythroid precursors osteoblasts proliferating cells pancreatic islet cells renal tubular cells oocytes activated lymphocytes granulosa cells theca cells cytotrophoblasts luteal cells myocytes syncytiotrophoblasts trophoblasts adrenal cortical cells adrenal medullary cells |
| gptkbp:foundIn |
gptkb:cell_membrane
|
| gptkbp:function |
mediates cellular uptake of transferrin-bound iron
|
| gptkbp:gene |
TFRC
|
| gptkbp:HGNC_ID |
gptkb:HGNC:11762
|
| https://www.w3.org/2000/01/rdf-schema#label |
CD71
|
| gptkbp:interactsWith |
gptkb:transferrin
|
| gptkbp:internalization |
clathrin-mediated endocytosis
|
| gptkbp:locatedOnChromosome |
chromosome 3q29
|
| gptkbp:molecularWeight |
~95 kDa
|
| gptkbp:OMIM |
190010
|
| gptkbp:significance |
overexpressed in many cancers
|
| gptkbp:structure |
type II transmembrane glycoprotein
|
| gptkbp:UniProtID |
P02786
|
| gptkbp:usedAs |
marker for cell proliferation
|
| gptkbp:bfsParent |
gptkb:RUNX1
gptkb:transferrin_receptor_1 |
| gptkbp:bfsLayer |
7
|