|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:GATA-2
gptkb:GATA-binding_factor_2
gptkb:NFE1B
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:acute_myeloid_leukemia
gptkb:Emberger_syndrome
gptkb:MonoMAC_syndrome
myelodysplastic syndrome
|
|
gptkbp:discoveredBy
|
gptkb:Stuart_H._Orkin
|
|
gptkbp:encodes
|
gptkb:GATA_binding_protein_2
|
|
gptkbp:Entrez_Gene_ID
|
2624
ENSG00000179348
|
|
gptkbp:expressedIn
|
endothelial cells
hematopoietic stem cells
|
|
gptkbp:function
|
transcription factor
regulation of hematopoiesis
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
4171
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
GATA2
|
|
gptkbp:interactsWith
|
gptkb:LMO2
gptkb:TAL1
gptkb:PU.1
gptkb:FOG1
|
|
gptkbp:length
|
480 amino acids
|
|
gptkbp:locatedOnChromosome
|
3q21.3
|
|
gptkbp:molecularWeight
|
50 kDa
|
|
gptkbp:mutationAssociatedWith
|
lymphedema
immunodeficiency
|
|
gptkbp:OMIM
|
137295
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Gata2
|
|
gptkbp:proteinFamily
|
gptkb:GATA_family
|
|
gptkbp:regulates
|
gptkb:GATA1
gptkb:CD34
gptkb:KIT
gptkb:EPOR
gptkb:FLT3
gptkb:MYB
gptkb:MPL
gptkb:RUNX1
gptkb:GATA_motif
gptkb:IL3RA
gptkb:SPI1
gene expression
immune system development
endothelial cell function
hematopoietic stem cell maintenance
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
|
|
gptkbp:UniProtID
|
P23769
|
|
gptkbp:bfsParent
|
gptkb:HBB
|
|
gptkbp:bfsLayer
|
6
|