Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alternativeSplicing |
membrane-bound CD14 (mCD14)
soluble CD14 (sCD14) |
| gptkbp:associatedWith |
sepsis
inflammatory response |
| gptkbp:biologicalProcess |
lipopolysaccharide binding
|
| gptkbp:cellularComponent |
gptkb:plasma_membrane
extracellular region |
| gptkbp:discoveredIn |
1980s
|
| gptkbp:encodedBy |
CD14 gene
|
| gptkbp:Entrez_Gene_ID |
929
|
| gptkbp:expressedIn |
dendritic cells
macrophages monocytes neutrophils |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
pattern recognition receptor
co-receptor for bacterial lipopolysaccharide (LPS) |
| gptkbp:HGNC_ID |
1628
|
| https://www.w3.org/2000/01/rdf-schema#label |
CD14
|
| gptkbp:interactsWith |
gptkb:TLR4
gptkb:MD-2 |
| gptkbp:involvedIn |
innate immune response
recognition of bacterial LPS |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_5
|
| gptkbp:OMIM |
158120
|
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Rattus_norvegicus |
| gptkbp:UniProtID |
P08571
|
| gptkbp:bfsParent |
gptkb:Macrophage
|
| gptkbp:bfsLayer |
5
|