Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
TIM-3
T-cell immunoglobulin and mucin-domain containing-3 |
| gptkbp:discoveredIn |
2002
|
| gptkbp:encodedBy |
HAVCR2 gene
|
| gptkbp:expressedIn |
gptkb:NK_cells
gptkb:T_cells dendritic cells monocytes |
| gptkbp:foundIn |
humans
|
| gptkbp:function |
regulation of immune response
immune checkpoint receptor |
| https://www.w3.org/2000/01/rdf-schema#label |
CD366
|
| gptkbp:involvedIn |
T cell exhaustion
|
| gptkbp:involves |
gptkb:cancer
autoimmune diseases chronic viral infections |
| gptkbp:ligand |
gptkb:CEACAM1
phosphatidylserine Galectin-9 |
| gptkbp:locatedOnChromosome |
chromosome 5q33.3
|
| gptkbp:molecularWeight |
~35 kDa
|
| gptkbp:structure |
mucin domain
IgV domain |
| gptkbp:target |
immunotherapy
|
| gptkbp:UniProtID |
Q8TDQ0
|
| gptkbp:bfsParent |
gptkb:immunoglobulin_superfamily
gptkb:RUNX1 |
| gptkbp:bfsLayer |
7
|