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gptkbp:instanceOf
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gptkb:disease
leukemia
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gptkbp:abbreviation
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gptkb:AML
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gptkbp:affects
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adults
blood
children
bone marrow
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gptkbp:causedBy
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genetic mutations
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gptkbp:commonIn
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older adults
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gptkbp:diagnosedBy
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blood test
bone marrow biopsy
cytogenetic analysis
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gptkbp:firstDescribed
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19th century
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gptkbp:hasGeneticMarker
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gptkb:CEBPA_mutation
gptkb:FLT3_mutation
gptkb:IDH1/2_mutation
gptkb:NPM1_mutation
gptkb:RUNX1_mutation
gptkb:t(8;21)_translocation
inv(16)
|
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https://www.w3.org/2000/01/rdf-schema#label
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acute myeloid leukemia
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gptkbp:ICD-10_code
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gptkb:C92.0
|
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gptkbp:mortalityRate
|
high
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gptkbp:originatedIn
|
myeloid lineage
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gptkbp:prevalence
|
rare
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gptkbp:prognosis
|
varies by subtype and patient factors
|
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gptkbp:riskFactor
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exposure to radiation
genetic disorders
myelodysplastic syndrome
exposure to benzene
previous chemotherapy
|
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gptkbp:subspecies
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gptkb:acute_erythroid_leukemia
gptkb:acute_megakaryoblastic_leukemia
gptkb:acute_monocytic_leukemia
gptkb:acute_myelomonocytic_leukemia
gptkb:acute_promyelocytic_leukemia
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gptkbp:symptom
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gptkb:anemia
fever
bleeding
fatigue
shortness of breath
easy bruising
frequent infections
pallor
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gptkbp:treatment
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supportive care
radiation therapy
chemotherapy
targeted therapy
stem cell transplant
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gptkbp:bfsParent
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gptkb:The_Cancer_Genome_Atlas
|
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gptkbp:bfsLayer
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4
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