Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:FLT3
gptkb:Fms-like_tyrosine_kinase_3 |
| gptkbp:discoveredIn |
1991
|
| gptkbp:encodedBy |
gptkb:FLT3_gene
|
| gptkbp:expressedIn |
hematopoietic progenitor cells
|
| gptkbp:function |
gptkb:receptor_tyrosine_kinase
cell surface receptor |
| gptkbp:HGNC_ID |
HGNC:3765
|
| https://www.w3.org/2000/01/rdf-schema#label |
CD135
|
| gptkbp:involvedIn |
cell differentiation
cell proliferation hematopoiesis |
| gptkbp:ligand |
FLT3 ligand
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_13
|
| gptkbp:molecularWeight |
~110 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:acute_myeloid_leukemia
myelodysplastic syndromes |
| gptkbp:target |
tyrosine kinase inhibitors
|
| gptkbp:transmembraneDomains |
true
|
| gptkbp:UniProtID |
P36888
|
| gptkbp:bfsParent |
gptkb:FLT3
gptkb:RUNX1 |
| gptkbp:bfsLayer |
7
|