|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:Cluster_of_Differentiation_34
gptkb:Hematopoietic_progenitor_cell_antigen_CD34
gp105-120
|
|
gptkbp:antibodyTarget
|
CD34 antibody
|
|
gptkbp:compatibleWith
|
mature blood cells
|
|
gptkbp:cytoplasmicDomain
|
short cytoplasmic tail
|
|
gptkbp:discoveredIn
|
1984
|
|
gptkbp:encodedBy
|
gptkb:CD34_gene
|
|
gptkbp:Entrez_Gene_ID
|
947
|
|
gptkbp:expressedIn
|
bone marrow
vascular endothelium
umbilical cord blood
embryonic fibroblasts
|
|
gptkbp:extracellularDomain
|
large, sialomucin domain
|
|
gptkbp:foundIn
|
humans
mice
|
|
gptkbp:function
|
cell surface receptor
cell adhesion
marker for hematopoietic stem cells
|
|
gptkbp:glycosylation
|
heavily glycosylated
|
|
gptkbp:HGNC_ID
|
HGNC:1663
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CD34
|
|
gptkbp:locatedOnChromosome
|
gptkb:human_chromosome_1
|
|
gptkbp:medicalUse
|
stem cell transplantation
diagnosis of leukemia
diagnosis of vascular tumors
|
|
gptkbp:molecularWeight
|
110 kDa
|
|
gptkbp:OMIM
|
142230
|
|
gptkbp:relatedTo
|
gptkb:CD45
gptkb:CD133
gptkb:CD38
leukemia
angiogenesis
myelodysplastic syndromes
hematopoiesis
CD34+ cells
CD34- cells
stem cell mobilization
|
|
gptkbp:structure
|
single-pass transmembrane protein
|
|
gptkbp:UniProtID
|
P28906
|
|
gptkbp:usedFor
|
mesenchymal stem cells
vascular endothelial cells
endothelial progenitor cells
hematopoietic progenitor cells
|
|
gptkbp:usedIn
|
immunohistochemistry
flow cytometry
|
|
gptkbp:bfsParent
|
gptkb:Epithelioid_Hemangioendothelioma
gptkb:GATA2
gptkb:MYB_proto-oncogene,_transcription_factor
gptkb:CD_antigens
gptkb:RUNX1
gptkb:pre-B-cell_acute_lymphoblastic_leukemia
|
|
gptkbp:bfsLayer
|
7
|