Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:leukocyte_common_antigen
|
| gptkbp:discoveredIn |
1970s
|
| gptkbp:encodedBy |
gptkb:PTPRC_gene
|
| gptkbp:expressedIn |
all differentiated hematopoietic cells except erythrocytes and plasma cells
|
| gptkbp:foundIn |
gptkb:leukocytes
|
| gptkbp:function |
regulation of T and B cell antigen receptor signaling
|
| gptkbp:hasIsoform |
gptkb:CD45RA
gptkb:CD45RABC gptkb:CD45RB gptkb:CD45RC gptkb:CD45RO |
| https://www.w3.org/2000/01/rdf-schema#label |
CD45
|
| gptkbp:isMarkerFor |
hematopoietic cells
|
| gptkbp:locatedOnChromosome |
1q31-q32
|
| gptkbp:location |
gptkb:cell_membrane
|
| gptkbp:molecularWeight |
180-220 kDa
|
| gptkbp:OMIM |
151460
|
| gptkbp:role |
signal transduction
autoimmune diseases leukemia diagnosis immune cell activation lymphocyte development |
| gptkbp:structure |
transmembrane protein tyrosine phosphatase
|
| gptkbp:target |
monoclonal antibodies
|
| gptkbp:UniProtID |
P08575
|
| gptkbp:usedIn |
immunophenotyping
|
| gptkbp:bfsParent |
gptkb:primary_effusion_lymphoma
|
| gptkbp:bfsLayer |
6
|