|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:B-lymphocyte_antigen_CD19
gptkb:Leu-12
B4
|
|
gptkbp:associatedWith
|
gptkb:B-cell_lymphomas
B-cell acute lymphoblastic leukemia
|
|
gptkbp:biologicalProcess
|
antigen binding
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
|
|
gptkbp:compatibleWith
|
gptkb:NK_cells
gptkb:T_cells
myeloid cells
|
|
gptkbp:discoveredIn
|
1980s
|
|
gptkbp:encodedBy
|
gptkb:CD19_gene
|
|
gptkbp:Entrez_Gene_ID
|
930
|
|
gptkbp:expressedIn
|
gptkb:lymphoid_tissue
B cell development
|
|
gptkbp:foundIn
|
gptkb:B_cells
|
|
gptkbp:function
|
B cell co-receptor
regulation of B cell activation
|
|
gptkbp:gene
|
gptkb:CD19
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:1633
|
|
gptkbp:interactsWith
|
gptkb:CD225
gptkb:CD21
gptkb:CD81
|
|
gptkbp:length
|
557
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_16
|
|
gptkbp:molecularWeight
|
61 kDa
|
|
gptkbp:OMIM
|
107265
|
|
gptkbp:orthologInMouse
|
Cd19
|
|
gptkbp:phosphorylates
|
tyrosine residues
|
|
gptkbp:regulates
|
B cell receptor signaling
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:target
|
gptkb:gene_therapy
gptkb:axicabtagene_ciloleucel
gptkb:blinatumomab
gptkb:tisagenlecleucel
gptkb:tafasitamab
gptkb:lisocabtagene_maraleucel
monoclonal antibodies
|
|
gptkbp:transmembraneDomains
|
yes
|
|
gptkbp:UniProtID
|
gptkb:P15391
|
|
gptkbp:usedAs
|
immunophenotyping marker
|
|
gptkbp:usedIn
|
gptkb:immunotherapy
diagnosis of B cell malignancies
monitoring minimal residual disease
|
|
gptkbp:bfsParent
|
gptkb:CR2
gptkb:JCAR014
gptkb:JCAR015
gptkb:JCAR017
gptkb:Monjuvi
gptkb:Tafasitamab
gptkb:CAR-T_cell_therapies
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CD19
|