|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:Erythroid_transcription_factor
gptkb:GF-1
gptkb:X-linked_thrombocytopenia_with_thalassemia_protein
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:acute_megakaryoblastic_leukemia
gptkb:Diamond-Blackfan_anemia
gptkb:X-linked_dyserythropoietic_anemia_and_thrombocytopenia
|
|
gptkbp:binds
|
gptkb:GATA_DNA_motif
|
|
gptkbp:discoveredBy
|
gptkb:Stuart_Orkin
|
|
gptkbp:discoveredIn
|
1989
|
|
gptkbp:encodes
|
gptkb:GATA1_protein
|
|
gptkbp:Entrez_Gene_ID
|
2623
|
|
gptkbp:expressedIn
|
gptkb:mast_cells
gptkb:eosinophils
gptkb:megakaryocytes
erythroid cells
|
|
gptkbp:fullName
|
gptkb:GATA_binding_protein_1
|
|
gptkbp:function
|
transcription factor
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
4170
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
GATA1
|
|
gptkbp:interactsWith
|
gptkb:EP300
gptkb:TAL1
gptkb:CBP
gptkb:FOG1
gptkb:LDB1
|
|
gptkbp:length
|
7 exons
|
|
gptkbp:locatedOnChromosome
|
gptkb:X_chromosome
gptkb:Xp11.23
|
|
gptkbp:mutationAssociatedWith
|
causes blood disorders
|
|
gptkbp:OMIM
|
305371
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Gata1
|
|
gptkbp:proteinFamily
|
zinc finger domain
|
|
gptkbp:regulates
|
eosinophil differentiation
erythroid differentiation
globin gene expression
hemoglobin gene expression
mast cell differentiation
megakaryocyte differentiation
platelet formation
|
|
gptkbp:transcriptionRegulatorOf
|
gptkb:HBB
gptkb:ALAS2
gptkb:GYPB
gptkb:ITGA2B
gptkb:NFE2
gptkb:PF4
|
|
gptkbp:UniProtID
|
P15976
|
|
gptkbp:bfsParent
|
gptkb:HBB
gptkb:HBB_gene
|
|
gptkbp:bfsLayer
|
6
|