|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:neprilysin
CALLA
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:endometrial_cancer
leukemia
prostate cancer
chronic lymphocytic leukemia
renal cell carcinoma
|
|
gptkbp:cellSurfaceMarker
|
gptkb:B_cells
granulocytes
some T cells
|
|
gptkbp:discoveredBy
|
Alan Bernard and colleagues
|
|
gptkbp:discoveredIn
|
1978
|
|
gptkbp:encodedBy
|
MME gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:CD10
|
|
gptkbp:enzymeCommissionNumber
|
EC 3.4.24.11
|
|
gptkbp:expressedIn
|
hematopoietic cells
stromal cells
epithelial cells
|
|
gptkbp:foundIn
|
gptkb:endometrium
gptkb:cancer
gptkb:kidney
gptkb:prostate
liver
breast tissue
lymphoid cells
|
|
gptkbp:function
|
zinc-dependent metalloprotease
degrades regulatory peptides
cell surface enzyme
|
|
gptkbp:gene
|
gptkb:MME
|
|
gptkbp:HGNC_ID
|
7156
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CD10
|
|
gptkbp:inhibitors
|
thiorphan
racecadotril
|
|
gptkbp:locatedOnChromosome
|
chromosome 3q25
|
|
gptkbp:location
|
gptkb:plasma_membrane
|
|
gptkbp:molecularWeight
|
100 kDa
|
|
gptkbp:OMIM
|
120520
|
|
gptkbp:role
|
regulation of blood pressure
neuropeptide degradation
peptide hormone metabolism
|
|
gptkbp:structure
|
type II transmembrane glycoprotein
|
|
gptkbp:UniProtID
|
P08473
|
|
gptkbp:usedAs
|
diagnostic marker in leukemia
diagnostic marker in lymphoma
diagnostic marker in some carcinomas
|
|
gptkbp:bfsParent
|
gptkb:B-cell_ALL
gptkb:MME
|
|
gptkbp:bfsLayer
|
6
|