CD123

GPTKB entity

Statements (18)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alsoKnownAs IL-3 receptor alpha chain
gptkbp:component interleukin-3 receptor
gptkbp:encodedBy IL3RA gene
gptkbp:expressedIn bone marrow
peripheral blood
gptkbp:foundIn gptkb:plasmacytoid_dendritic_cells
hematopoietic stem cells
leukemic blasts in acute myeloid leukemia
gptkbp:function binds interleukin-3
https://www.w3.org/2000/01/rdf-schema#label CD123
gptkbp:locatedOnChromosome gptkb:Xp22.3
gptkbp:molecularWeight ~60 kDa
gptkbp:structure single-pass type I membrane protein
gptkbp:target immunotherapy in leukemia
gptkbp:usedAs biomarker in hematological malignancies
gptkbp:bfsParent gptkb:RUNX1
gptkbp:bfsLayer 7