|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:AML1
gptkb:CBFA2
|
|
gptkbp:associatedWith
|
gptkb:acute_myeloid_leukemia
gptkb:familial_platelet_disorder_with_propensity_to_myeloid_malignancy
|
|
gptkbp:discoveredBy
|
gptkb:Yoshida_et_al.
|
|
gptkbp:domain
|
Runt domain
|
|
gptkbp:encodes
|
runt-related transcription factor 1
|
|
gptkbp:Entrez_Gene_ID
|
861
ENSG00000159216
|
|
gptkbp:expressedIn
|
hematopoietic stem cells
|
|
gptkbp:GO_term
|
gptkb:GO:0008283
GO:0005515
GO:0005634
GO:0003677
GO:0003700
GO:0006355
GO:0006366
GO:0045944
GO:0001227
GO:0001228
GO:0045893
|
|
gptkbp:hasTranscriptVariant
|
Runx1a
Runx1b
Runx1c
|
|
gptkbp:HGNC_ID
|
10471
|
|
gptkbp:interactsWith
|
gptkb:CBFβ
|
|
gptkbp:involvedIn
|
embryonic development
hematopoiesis
lymphocyte development
megakaryocyte differentiation
myeloid cell differentiation
|
|
gptkbp:locatedOnChromosome
|
chromosome 21
|
|
gptkbp:memberOf
|
gptkb:RUNX_family
|
|
gptkbp:mutationAssociatedWith
|
leukemogenesis
|
|
gptkbp:OMIM
|
151385
|
|
gptkbp:orthologIn
|
RUNX1 (human)
Runx1 (mouse)
|
|
gptkbp:PDB
|
1H9D
1IO3
1IO4
1LJM
|
|
gptkbp:regulates
|
apoptosis
cell differentiation
cell proliferation
transcription of target genes
|
|
gptkbp:transcriptionFactorFor
|
gptkb:gene
|
|
gptkbp:UniProtID
|
Q01196
|
|
gptkbp:bfsParent
|
gptkb:RUNX1
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Runx1
|