Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alsoKnownAs |
fatty acid translocase
platelet glycoprotein 4 |
| gptkbp:associatedWith |
gptkb:metabolic_syndrome
atherosclerosis insulin resistance thrombocytopenia malaria resistance |
| gptkbp:discoveredBy |
T. Endemann et al.
|
| gptkbp:discoveredIn |
1993
|
| gptkbp:encodedBy |
CD36 gene
|
| gptkbp:Entrez_Gene_ID |
948
ENSG00000135218 |
| gptkbp:expressedIn |
macrophages
platelets endothelial cells muscle cells monocytes adipocytes |
| gptkbp:foundIn |
humans
mice |
| gptkbp:function |
cell adhesion
fatty acid uptake scavenger receptor activity oxidized LDL uptake |
| gptkbp:HGNC_ID |
1663
|
| https://www.w3.org/2000/01/rdf-schema#label |
CD36
|
| gptkbp:interactsWith |
collagen
long-chain fatty acids thrombospondin-1 oxidized phospholipids |
| gptkbp:locatedOnChromosome |
7q21.11
|
| gptkbp:location |
gptkb:plasma_membrane
intracellular vesicles |
| gptkbp:memberOf |
scavenger receptor class B family
|
| gptkbp:mutationAssociatedWith |
increased risk of type 2 diabetes
CD36 deficiency platelet glycoprotein IV deficiency |
| gptkbp:OMIM |
173510
|
| gptkbp:orthologIn |
mouse Cd36
rat Cd36 zebrafish cd36 |
| gptkbp:PDB |
5LGD
|
| gptkbp:regulates |
lipid metabolism
angiogenesis inflammatory response |
| gptkbp:target |
antibodies in immune thrombocytopenia
therapeutic drugs for metabolic diseases |
| gptkbp:UniProtID |
P16671
|
| gptkbp:bfsParent |
gptkb:PfEMP1
|
| gptkbp:bfsLayer |
6
|