|
gptkbp:instanceOf
|
transcription factor
|
|
gptkbp:activatedBy
|
gptkb:JNK_signaling_pathway
gptkb:MAPK_signaling_pathway
gptkb:ERK_signaling_pathway
|
|
gptkbp:binds
|
gptkb:gene
|
|
gptkbp:composedOf
|
gptkb:Fos_protein_family
gptkb:Jun_protein_family
|
|
gptkbp:discoveredIn
|
1987
|
|
gptkbp:foundIn
|
eukaryotic cells
|
|
gptkbp:fullName
|
gptkb:Activator_Protein_1
|
|
gptkbp:function
|
apoptosis
cell differentiation
cell proliferation
regulation of gene expression
|
|
gptkbp:gene
|
gptkb:AP1
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
AP1
|
|
gptkbp:involvedIn
|
cancer progression
inflammation
immune response
|
|
gptkbp:recognizesMotif
|
gptkb:TRE_(TPA_response_element)
|
|
gptkbp:regulates
|
gptkb:Bcl-2
gptkb:EGFR
gptkb:ICAM-1
gptkb:cyclin_D1
gptkb:TNF-alpha
gptkb:GM-CSF
gptkb:E-selectin
gptkb:MCP-1
gptkb:p21
gptkb:COX-2
gptkb:c-Myc
gptkb:p53
gptkb:IL-2
gptkb:CD44
gptkb:TGF-beta
gptkb:FasL
gptkb:VEGF
gptkb:IL-8
cell cycle genes
cytokine genes
MMP genes
growth factor genes
|
|
gptkbp:subunit
|
gptkb:c-Jun
gptkb:FosB
gptkb:Fra-1
gptkb:Fra-2
gptkb:JunD
gptkb:c-Fos
gptkb:JunB
|
|
gptkbp:bfsParent
|
gptkb:Honda_S2000
|
|
gptkbp:bfsLayer
|
6
|