Statements (66)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:Oni
|
| gptkbp:associated_with |
apoptosis
cell growth cell proliferation tumorigenesis |
| gptkbp:challenges |
leads to cell death
|
| gptkbp:genetic_studies |
associated with cancer
|
| https://www.w3.org/2000/01/rdf-schema#label |
c-Myc
|
| gptkbp:initiated_by |
Myc inhibitors
|
| gptkbp:interacts_with |
gptkb:Max
gptkb:p53 Mxd1 |
| gptkbp:involved_in |
gptkb:developers
gptkb:Oncology gptkb:embryonic_development DNA replication metabolism cellular homeostasis cellular metabolism cellular stress response chromatin remodeling immune response signal transduction cellular response to stress cellular aging cellular differentiation differentiation neurogenesis angiogenesis cellular signaling pathways stem cell maintenance cellular signaling transcriptional regulation tissue homeostasis hematopoiesis cellular repair mechanisms cellular response to DNA damage cellular growth control cellular metabolism regulation cellular response to cytokines cellular response to hormones cellular response to hypoxia cellular response to oxidative stress neoplastic transformation cellular apoptosis cellular response to growth factors cellular response to inflammation cellular response to metabolic stress cellular response to nutrients cellular response to environmental signals cellular response to growth signals cellular response to stress signals cellular differentiation control cellular proliferation control cellular response to death factors cellular response to death signals cellular response to survival factors cellular response to survival signals |
| gptkbp:is_expressed_in |
various tissues
|
| gptkbp:is_targeted_at |
therapeutic strategies
|
| gptkbp:located_in |
gptkb:Atom
|
| gptkbp:overexpression |
linked to poor prognosis
|
| gptkbp:regulates |
gene expression
|
| gptkbp:role |
cell cycle progression
|
| gptkbp:bfsParent |
gptkb:Yamanaka_factors
|
| gptkbp:bfsLayer |
4
|