Statements (60)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:vaccine
|
| gptkbp:associated_with |
autoimmune diseases
fibrosis cancer progression |
| gptkbp:established |
small molecule inhibitors
TGF-beta receptor inhibitors |
| gptkbp:function |
regulates cell growth
involved in immune response inhibits inflammation promotes tissue repair |
| https://www.w3.org/2000/01/rdf-schema#label |
TGF-beta
|
| gptkbp:is_a_route_for |
SMAD signaling pathway
non-SMAD signaling pathways |
| gptkbp:is_involved_in |
gptkb:cystic_fibrosis
gptkb:Crohn's_disease gptkb:systemic_lupus_erythematosus gptkb:ulcerative_colitis gptkb:psychologist gptkb:motorcycle gptkb:rheumatoid_arthritis apoptosis cell cycle regulation liver diseases metabolic disorders dermatitis cardiovascular diseases cellular senescence chronic kidney disease tumor microenvironment immune tolerance psoriasis skin diseases pulmonary fibrosis atherosclerosis chronic inflammation aging process metastasis stem cell maintenance kidney diseases gastrointestinal diseases pulmonary diseases muscle disorders tissue homeostasis endocrine disorders reproductive disorders diabetes complications obesity-related inflammation |
| gptkbp:is_vulnerable_to |
gptkb:TGF-beta_receptor_type_I
gptkb:TGF-beta_receptor_type_II |
| gptkbp:location |
extracellular space
|
| gptkbp:produced_by |
platelets
fibroblasts macrophages |
| gptkbp:role |
gptkb:embryonic_development
cell differentiation wound healing angiogenesis extracellular matrix production |
| gptkbp:bfsParent |
gptkb:T-helper_17_cells
|
| gptkbp:bfsLayer |
6
|