Fos protein family

GPTKB entity

Statements (31)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:activatedBy cytokines
growth factors
stress signals
gptkbp:discoveredBy 1980s
gptkbp:domain basic leucine zipper domain
gptkbp:expressedIn mammals
vertebrates
gptkbp:form AP-1 transcription factor complex
gptkbp:formsComplexWith gptkb:Jun_protein_family
gptkbp:function transcription factor
gptkbp:gene gptkb:FOSB
gptkb:FOSL1
gptkb:FOSL2
gptkb:FOS
https://www.w3.org/2000/01/rdf-schema#label Fos protein family
gptkbp:involves gptkb:cancer
neurodegenerative diseases
osteosarcoma
gptkbp:member gptkb:FosB
gptkb:Fra-1
gptkb:Fra-2
gptkb:c-Fos
gptkbp:regulates apoptosis
cell differentiation
cell proliferation
immune response
neuronal activity
gptkbp:subcellularLocation gptkb:nucleus
gptkbp:bfsParent gptkb:AP1
gptkbp:bfsLayer 7