|
gptkbp:instanceOf
|
biological pathway
|
|
gptkbp:activatedBy
|
stress
cytokines
growth factors
|
|
gptkbp:alsoKnownAs
|
gptkb:Mitogen-activated_protein_kinase_pathway
|
|
gptkbp:component
|
gptkb:ERK5_pathway
gptkb:ERK_pathway
gptkb:JNK_pathway
gptkb:p38_MAPK_pathway
|
|
gptkbp:dysregulationAssociatedWith
|
gptkb:cancer
neurodegenerative diseases
inflammatory diseases
|
|
gptkbp:foundIn
|
eukaryotes
|
|
gptkbp:hasBiologicalActivity
|
gptkb:MAP2K1
gptkb:MAPK1
gptkb:MAPK3
gptkb:MEK1
gptkb:MEK2
gptkb:JNK1
gptkb:JNK2
gptkb:MAP2K2
gptkb:MAP3K1
gptkb:MAPK14
gptkb:MAPK8
gptkb:p38_alpha
gptkb:p38_beta
gptkb:p38_delta
gptkb:p38_gamma
gptkb:BRAF
gptkb:RAF1
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MAPK signaling pathway
|
|
gptkbp:inhibitedBy
|
gptkb:PD98059
gptkb:U0126
gptkb:SB203580
gptkb:SP600125
|
|
gptkbp:involves
|
MAPK proteins
MAPKK proteins
MAPKKK proteins
|
|
gptkbp:KEGGID
|
hsa04010
|
|
gptkbp:Reactome
|
gptkb:R-HSA-5673001
|
|
gptkbp:regulates
|
apoptosis
cell differentiation
cell proliferation
cell survival
gene expression
|
|
gptkbp:studiedIn
|
cancer research
immunology
neuroscience
|
|
gptkbp:WikiPathways_ID
|
WP382
|
|
gptkbp:bfsParent
|
gptkb:Drosophila_Ras85D
gptkb:RalGDS
gptkb:UniProt:P01112
gptkb:F-BVFA
gptkb:RET_proto-oncogene
gptkb:BRAF_gene
|
|
gptkbp:bfsLayer
|
5
|