|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:Hermes_antigen
gptkb:Pgp-1
gptkb:lymphocyte_homing_receptor
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
autoimmune diseases
inflammation
cancer metastasis
|
|
gptkbp:chromosomeArm
|
gptkb:11p13
|
|
gptkbp:component
|
gptkb:plasma_membrane
|
|
gptkbp:discoveredBy
|
gptkb:Steven_A._Stacker
|
|
gptkbp:encodedBy
|
gptkb:CD44_gene
|
|
gptkbp:Entrez_Gene_ID
|
960
|
|
gptkbp:expressedIn
|
cancer cells
hematopoietic cells
epithelial cells
|
|
gptkbp:function
|
gptkb:hyaluronic_acid_receptor
cell migration
cell adhesion
hyaluronic acid binding
lymphocyte activation
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GOProcess
|
cell-cell adhesion
leukocyte migration
|
|
gptkbp:hasBiomarker
|
cancer stem cells
|
|
gptkbp:hasIsoform
|
gptkb:CD44_standard
gptkb:CD44_variant
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
HGNC:1681
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CD44
|
|
gptkbp:interactsWith
|
gptkb:osteopontin
gptkb:matrix_metalloproteinases
collagen
hyaluronic acid
|
|
gptkbp:length
|
742 amino acids (standard isoform)
|
|
gptkbp:locatedOnChromosome
|
11
|
|
gptkbp:molecularWeight
|
80-200 kDa
|
|
gptkbp:OMIM
|
107269
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:postTranslationalModification
|
phosphorylation
glycosylation
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:structure
|
single-pass type I membrane protein
|
|
gptkbp:subcellularLocation
|
gptkb:plasma_membrane
|
|
gptkbp:target
|
gptkb:cancer
|
|
gptkbp:transmembraneDomains
|
yes
|
|
gptkbp:UniProtID
|
P16070
|
|
gptkbp:bfsParent
|
gptkb:EGR1
|
|
gptkbp:bfsLayer
|
6
|