|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:CD95L
CD178
|
|
gptkbp:discoveredIn
|
1993
|
|
gptkbp:encodedBy
|
gptkb:FASLG_gene
|
|
gptkbp:expressedIn
|
gptkb:natural_killer_cells
activated T cells
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:fullName
|
gptkb:Fas_ligand
|
|
gptkbp:function
|
induces apoptosis
|
|
gptkbp:HGNC_ID
|
11936
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
FasL
|
|
gptkbp:inducedBy
|
cell death
|
|
gptkbp:interactsWith
|
Fas receptor (CD95)
|
|
gptkbp:involvedIn
|
peripheral tolerance
activation-induced cell death (AICD)
cytotoxic T lymphocyte function
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_1q23
|
|
gptkbp:memberOf
|
tumor necrosis factor (TNF) family
|
|
gptkbp:molecularWeight
|
40 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:autoimmune_lymphoproliferative_syndrome_(ALPS)
|
|
gptkbp:OMIM
|
134638
|
|
gptkbp:recipient
|
gptkb:Fas_receptor
|
|
gptkbp:role
|
gptkb:cancer
autoimmune disease
immune system regulation
immune privilege
|
|
gptkbp:species
|
gptkb:human
gptkb:mouse
right
|
|
gptkbp:structure
|
type-II transmembrane protein
|
|
gptkbp:UniProtID
|
gptkb:P48023
|
|
gptkbp:bfsParent
|
gptkb:FOXO
gptkb:c-Jun
gptkb:AP1
|
|
gptkbp:bfsLayer
|
7
|