Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:protein
|
| gptkbp:bfsLayer |
6
|
| gptkbp:bfsParent |
gptkb:cyclin_D
|
| gptkbp:associated_with |
gptkb:myelodysplastic_syndromes
gptkb:neurofibromatosis_type_1 gptkb:healthcare_organization gptkb:hepatocellular_carcinoma gptkb:head_and_neck_squamous_cell_carcinoma gptkb:non-Hodgkin_lymphoma gptkb:neuroblastoma ovarian cancer endometrial cancer esophageal cancer bladder cancer neuroendocrine tumors thymoma germ cell tumors adrenocortical carcinoma carcinoid tumors chordoma |
| gptkbp:clinical_trial |
biomarker for cancer prognosis
|
| gptkbp:compression_ratio |
can lead to cell cycle arrest
|
| gptkbp:discovered_by |
David Beach
|
| gptkbp:established |
RNA interference
monoclonal antibodies small molecule inhibitors p16 IN K4a p21 CI P1 |
| gptkbp:exemplifies |
leads to cancer progression
|
| gptkbp:function |
regulates cell cycle progression
|
| gptkbp:genetic_diversity |
associated with tumorigenesis
|
| gptkbp:habitat |
11q13
|
| https://www.w3.org/2000/01/rdf-schema#label |
cyclin D1
|
| gptkbp:intelligence |
found in many species
|
| gptkbp:interacts_with |
CD K6
CD K4 |
| gptkbp:is_a_route_for |
MAPK pathway
Ras signaling pathway P I3 K/ AKT pathway |
| gptkbp:is_involved_in |
apoptosis regulation
cell differentiation cell proliferation |
| gptkbp:is_represented_in |
varies in different tissues
regulated by growth factors |
| gptkbp:location |
gptkb:physicist
|
| gptkbp:promoter |
CCN D1
|
| gptkbp:research |
target for cancer therapy
|
| gptkbp:role |
G1 phase of cell cycle
promotes oncogenesis |
| gptkbp:type |
gptkb:species
|
| gptkbp:weight |
36 k Da
|
| gptkbp:year_created |
gptkb:1992
|