Statements (28)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:alternativeName |
gptkb:BCL1
gptkb:PRAD1 U21B31 |
gptkbp:associatedWith |
gptkb:cancer
|
gptkbp:binds |
gptkb:CDK4
gptkb:CDK6 |
gptkbp:degradedBy |
gptkb:ubiquitin-proteasome_pathway
|
gptkbp:discoveredIn |
1991
|
gptkbp:encodedBy |
gptkb:CCND1_gene
|
gptkbp:function |
regulation of cell cycle
G1/S cell cycle transition |
https://www.w3.org/2000/01/rdf-schema#label |
cyclin D1
|
gptkbp:locatedOnChromosome |
gptkb:11q13
|
gptkbp:location |
gptkb:nucleus
gptkb:cytoplasm |
gptkbp:molecularWeight |
36 kDa
|
gptkbp:overexpressedIn |
gptkb:mantle_cell_lymphoma
gptkb:cancer |
gptkbp:phosphorylates |
gptkb:GSK3β
|
gptkbp:regulates |
RB1 phosphorylation
|
gptkbp:role |
cell proliferation
oncogenesis |
gptkbp:species |
gptkb:Homo_sapiens
|
gptkbp:target |
anticancer drugs
|
gptkbp:UniProtID |
P24385
|
gptkbp:bfsParent |
gptkb:GSK3
|
gptkbp:bfsLayer |
6
|