|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:PU.1
SFFV proviral integration 1
|
|
gptkbp:associatedWith
|
gptkb:acute_myeloid_leukemia
immunodeficiency
|
|
gptkbp:bindsDNASequence
|
PU-box (5'-GAGGAA-3')
|
|
gptkbp:chromosomeArm
|
gptkb:11p11.2
|
|
gptkbp:encodes
|
gptkb:PU.1
|
|
gptkbp:Entrez_Gene_ID
|
6688
ENSG00000185551
|
|
gptkbp:expressedIn
|
hematopoietic cells
|
|
gptkbp:function
|
transcription factor
regulation of hematopoiesis
|
|
gptkbp:HGNC_ID
|
11205
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SPI1
|
|
gptkbp:interactsWith
|
gptkb:GATA1
gptkb:CBP/p300
gptkb:IRF4
|
|
gptkbp:length
|
272 amino acids
|
|
gptkbp:locatedOnChromosome
|
11
|
|
gptkbp:molecularWeight
|
31 kDa
|
|
gptkbp:mutationAssociatedWith
|
hematological malignancies
|
|
gptkbp:OMIM
|
165170
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Spi1
|
|
gptkbp:regulates
|
gptkb:CD32
gptkb:CD20
gptkb:CD45
gptkb:CD79a
gptkb:CD34
gptkb:CD33
gptkb:CD127
gptkb:ETS_family
gptkb:CD19
gptkb:CD14
gptkb:CD11b
gptkb:CD123
gptkb:CD135
gptkb:CSF1R
gptkb:CD300
gptkb:CD302
gptkb:CD303
gptkb:CD304
gptkb:CD305
gptkb:CD306
gptkb:CD307
gptkb:CD308
gptkb:CD309
gptkb:CD310
gptkb:CD311
gptkb:CD312
gptkb:CD313
gptkb:CD314
gptkb:CD315
gptkb:CD316
gptkb:CD317
gptkb:CD318
gptkb:CD319
gptkb:CD320
gptkb:CD321
gptkb:CD322
gptkb:CD323
gptkb:CD324
gptkb:CD325
gptkb:CD326
gptkb:CD327
gptkb:CD328
gptkb:CD329
gptkb:CD330
gptkb:CD331
gptkb:CD332
gptkb:CD333
gptkb:CD334
gptkb:CD335
gptkb:CD336
gptkb:CD337
gptkb:CD338
gptkb:CD339
gptkb:CD340
gptkb:CD86
gptkb:CD200
gptkb:CD344
gptkb:CD349
gptkb:CD350
B cell development
CD16
CD68
IL7R
GM-CSF receptor
myeloid cell differentiation
CD115
M-CSF receptor
CD150
CD163
CD341
CD342
CD343
CD345
CD346
CD347
CD348
CD64
macrophage development
|
|
gptkbp:UniProtID
|
P17947
|
|
gptkbp:bfsParent
|
gptkb:GATA2
|
|
gptkbp:bfsLayer
|
7
|