|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:EpCAM
gptkb:Epithelial_Cell_Adhesion_Molecule
|
|
gptkbp:antibodyClone
|
gptkb:ESA
gptkb:AUA1
gptkb:Ber-EP4
gptkb:EBA-1
gptkb:EpCAM-1
gptkb:EpCAM-2
gptkb:EpCAM-3
gptkb:HEA125
gptkb:MOC31
gptkb:VU-1D9
323/A3
G8.8
KS1/4
|
|
gptkbp:associatedWith
|
gptkb:cancer
prostate cancer
colon cancer
carcinomas
|
|
gptkbp:cellSurfaceMarker
|
true
|
|
gptkbp:discoveredIn
|
1979
|
|
gptkbp:encodedBy
|
gptkb:EPCAM_gene
|
|
gptkbp:expressedIn
|
epithelial tissues
|
|
gptkbp:function
|
cell differentiation
cell proliferation
cell signaling
cell adhesion
|
|
gptkbp:gene
|
gptkb:EPCAM
|
|
gptkbp:HGNC_ID
|
HGNC:970
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CD326
|
|
gptkbp:involvedIn
|
gptkb:Wnt_signaling_pathway
regulation of cell migration
cell-cell adhesion
|
|
gptkbp:length
|
314 amino acids
|
|
gptkbp:locatedOnChromosome
|
2p21
|
|
gptkbp:MIMNumber
|
185535
|
|
gptkbp:molecularWeight
|
35-40 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:hereditary_nonpolyposis_colorectal_cancer
gptkb:congenital_tufting_enteropathy
|
|
gptkbp:structure
|
single-pass type I membrane protein
|
|
gptkbp:target
|
immunotherapy
therapeutic antibodies
|
|
gptkbp:UniProtID
|
P16422
|
|
gptkbp:usedAs
|
biomarker
cancer stem cell marker
|
|
gptkbp:usedIn
|
immunohistochemistry
flow cytometry
|
|
gptkbp:bfsParent
|
gptkb:EPCAM
|
|
gptkbp:bfsLayer
|
6
|