Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:KDR
gptkb:VEGFR-2 gptkb:Flk-1 |
| gptkbp:binds |
gptkb:vascular_endothelial_growth_factor_(VEGF)
|
| gptkbp:encodedBy |
gptkb:KDR_gene
|
| gptkbp:expressedIn |
gptkb:cancer
gptkb:skeletal_muscle gptkb:kidney gptkb:placenta heart endothelial cells |
| gptkbp:foundIn |
humans
|
| gptkbp:function |
gptkb:receptor_tyrosine_kinase
|
| gptkbp:HGNC_ID |
HGNC:6307
|
| https://www.w3.org/2000/01/rdf-schema#label |
CD309
|
| gptkbp:involvedIn |
embryonic development
wound healing tumor growth |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_4q12
|
| gptkbp:molecularWeight |
approximately 200 kDa
|
| gptkbp:OMIM |
191306
|
| gptkbp:phosphorylates |
autophosphorylation upon ligand binding
|
| gptkbp:role |
angiogenesis
vasculogenesis |
| gptkbp:structure |
single-pass type I membrane protein
|
| gptkbp:target |
monoclonal antibodies
tyrosine kinase inhibitors anti-angiogenic cancer therapies |
| gptkbp:UniProtID |
P35968
|
| gptkbp:bfsParent |
gptkb:VEGFR2
|
| gptkbp:bfsLayer |
6
|