Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:ITGAM
integrin alpha M |
| gptkbp:associatedWith |
gptkb:systemic_lupus_erythematosus
gptkb:leukocyte_adhesion_deficiency_type_1 autoimmune diseases |
| gptkbp:binds |
gptkb:ICAM-1
gptkb:fibrinogen gptkb:iC3b gptkb:factor_X |
| gptkbp:discoveredIn |
1980s
|
| gptkbp:encodedBy |
gptkb:ITGAM_gene
|
| gptkbp:expressedIn |
gptkb:natural_killer_cells
dendritic cells macrophages monocytes granulocytes |
| gptkbp:familyMember |
integrin family
|
| gptkbp:form |
gptkb:Mac-1_integrin
|
| gptkbp:formsComplexWith |
gptkb:CD18
|
| gptkbp:function |
phagocytosis
cell adhesion immune response regulation leukocyte migration |
| https://www.w3.org/2000/01/rdf-schema#label |
CD11b
|
| gptkbp:locatedOnChromosome |
gptkb:16p11.2
|
| gptkbp:marking |
gptkb:microglia
myeloid cells |
| gptkbp:molecularWeight |
170 kDa
|
| gptkbp:structure |
transmembrane glycoprotein
|
| gptkbp:usedIn |
flow cytometry
|
| gptkbp:bfsParent |
gptkb:microglia
|
| gptkbp:bfsLayer |
6
|