ETS family

GPTKB entity

Statements (58)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alsoKnownAs E26 transformation-specific family
gptkbp:binds gptkb:gene
GGAA/T core motif
gptkbp:contains gptkb:ETS_domain
gptkbp:discoveredBy gptkb:Pierre_Chambon
gptkbp:domain winged helix-turn-helix
gptkbp:foundIn animals
fungi
some plants
gptkbp:function transcription factor
https://www.w3.org/2000/01/rdf-schema#label ETS family
gptkbp:involvedIn apoptosis
cell differentiation
cell proliferation
tumorigenesis
gptkbp:member gptkb:ELK1
gptkb:SPIC
gptkb:EHF
gptkb:ERG
gptkb:ETS1
gptkb:ETS2
gptkb:GABPA
gptkb:SPI1
gptkb:ETV6
gptkb:FLI1
TEL
FEV
ETV1
ETV4
ETV5
SPIB
ELF1
ELF2
ELF3
ELF4
ELF5
ETV7
PDEF
SPDEF
gptkbp:mutationAssociatedWith gptkb:cancer
gptkb:Ewing's_sarcoma
leukemia
prostate cancer
gptkbp:namedAfter E26 avian leukemia virus
gptkbp:numberOfMembers 28 in humans
gptkbp:regulates gene expression
gptkbp:superfamily transcription factors
gptkbp:bfsParent gptkb:ETV2
gptkb:ETS1
gptkb:GABPA
gptkb:PU.1
gptkb:SPI1
gptkb:ETV6
gptkb:EWSR1-FLI1
gptkb:ETV6_gene
gptkb:TEL_gene
gptkbp:bfsLayer 8